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Theodor Kocher (1841-1917), an exceptional Swiss surgeon who described a technique for the safe removal of enlarged thyroid unraveled the true function of this endocrine gland but also made significant contributions to many other fields of surgery. Kocher was the first surgeon awarded the Nobel prize in Physiology and Medicine in 1909 for his work on the physiology, pathology, and surgery of the thyroid gland. He was professor and clinical director at Insel Hospital during 45 years. Kocher created the prominent Surgeon's School in Bern. He was the first president of the International Society of Surgery in 1903 and the founding president of the Swiss Society of Surgery in 1913.

With the majority of eponyms being removed from disease classification systems, it is even more difficult to remember the neurologists who influenced the development of techniques and understanding of the brain over the last centuries. Determining whether Polish researchers were given similar attention to Western equivalents based on eponymic presence in medical databases is an interesting way to provide an overview of unremembered Polish neurologists. This work aims to recognize the developments of forgotten Polish neurologists, whose work, although important, was not properly appreciated over the centuries.

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This article describes the organization, operation, and contents of the Virtual Historical Archive of the Faculty of Psychology, University of Buenos Aires, Argentina. The organization of this archive started in 2008, as part of the activities planned by the Chair II of History of Psychology, and gained the support of the Faculty of Psychology. From its beginnings to the present, several documentary sources and materials related to the history of psychology in Argentina have been incorporated. It currently contains six thematic sections and three special collections, and it is expected that in the future it will be extended to other thematic areas. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

The search for melatonin receptor agonists formed the main part of melatonin medicinal chemistry programs for the last three decades. In this short review, we summarize the two main aspects of these programs: the development of all the necessary tools to characterize the newly synthesized ligands at the two melatonin receptors MT 1 and MT 2 , and the medicinal chemist's approaches to find chemically diverse ligands at these receptors. Both strategies are described. It turns out that the main source of tools were industrial laboratories, while the medicinal chemistry was mainly carried out in academia. Such complete accounts are interesting, as they delineate the spirits in which the teams were working demonstrating their strength and innovative character. Most of the programs were focused on nonselective agonists and few of them reached the market. In contrast, discovery of MT 1 -selective agonists and melatonergic antagonists with proven in vivo activity and MT 1 or MT 2 -selectivity is still in its infancy, despite the considerable interest that subtype selective compounds may bring in the domain, as the physiological respective roles of the two subtypes of melatonin receptors, is still poorly understood. Poly-pharmacology applications and multitarget ligands have also been considered., (© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

This historical note describes the book Primer in critical personalism: A framework for reviving psychological inquiry and for grounding a socio-cultural ethos by James T. Lamiell. The overriding purpose of this book is to introduce psychologists, other social scientists, and thoughtful laypersons to that comprehensive system of thought developed by the German philosopher and psychologist William Stern (1871-1938) under the name "critical personalism." (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Recent discoveries related to the habitability and astrobiological relevance of the outer Solar System have expanded our understanding of where and how life may have originated. As a result, the Icy Worlds of the outer Solar System have become among the highest priority targets for future spacecraft missions dedicated to astrobiology-focused and/or direct life detection objectives. This, in turn, has led to a renewed interest in planetary protection concerns and policies for the exploration of these worlds and has been a topic of discussion within the COSPAR (Committee on Space Research) Panel on Planetary Protection. This paper summarizes the results of those discussions, reviewing the current knowledge and the history of planetary protection considerations for Icy Worlds as well as suggesting ways forward. Based on those discussions, we therefore suggest to (1) Establish a new definition for Icy Worlds for Planetary Protection that captures the outer Solar System moons and dwarf planets like Pluto, but excludes more primitive bodies such as comets, centaurs, and asteroids: Icy Worlds in our Solar System are defined as all bodies with an outermost layer that is believed to be greater than 50 % water ice by volume and have enough mass to assume a nearly round shape. (2) Establish indices for the lower limits of Earth life with regards to water activity (LLAw) and temperature (LLT) and apply them into all areas of the COSPAR Planetary Protection Policy. These values are currently set at 0.5 and -28 °C and were originally established for defining Mars Special Regions; (3) Establish LLT as a parameter to assign categorization for Icy Worlds missions. The suggested categorization will have a 1000-year period of biological exploration, to be applied to all Icy Worlds and not just Europa and Enceladus as is currently the case. (4) Have all missions consider the possibility of impact. Transient thermal anomalies caused by impact would be acceptable so long as there is less than 10 -4 probability of a single microbe reaching deeper environments where temperature is >LLT in the period of biological exploration. (5) Restructure or remove Category II* from the policy as it becomes largely redundant with this new approach, (6) Establish that any sample return from an Icy World should be Category V restricted Earth return., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier B.V.)

Across 133 confirmed mpox zoonotic index cases reported during 1970-2021 in Africa, cases occurred year-round near the equator, where climate is consistent. However, in tropical regions of the northern hemisphere under a dry/wet season cycle, cases occurred seasonally. Our findings further support the seasonality of mpox zoonotic transmission risk.

Competing Interests: Disclosures None.

Competing Interests: The author declares no conflict of interest.

Early in the twentieth century, Walter B. Cannon (1871-1945) introduced his overarching hypothesis of "homeostasis" (Cannon 1932)-the ability to sustain physiological values within a narrow range necessary for life during periods of stress. Physical exercise represents a stress in which motor, respiratory and cardiovascular systems must be integrated across a range of metabolic stress to match oxygen delivery to oxygen need at the cellular level, together with appropriate thermoregulatory control, blood pressure adjustments and energy provision. Of these, blood pressure regulation is a complex but controlled variable, being the function of cardiac output and vascular resistance (or conductance). Key in understanding blood pressure control during exercise is the coordinating role of the autonomic nervous system. A long history outlines the development of these concepts and how they are integrated within the exercise context. This review focuses on the renaissance observations and thinking generated in the first three decades of the twentieth century that opened the doorway to new concepts of inquiry in cardiovascular regulation during exercise. The concepts addressed here include the following: (1) exercise and blood pressure, (2) central command, (3) neurovascular transduction with emphasis on the sympathetic nerve activity and the vascular end organ response, and (4) tonic neurovascular integration., (© 2024. The Author(s).)

The study examines the development of psychology in former Czechoslovakia during the period of "normalization" (1968-1989) and the challenges it faced under the communist regime. The restricted connection to Western psychology and the regime's control over all aspects of human activity negatively influenced the continuity of development in psychology. The regime demanded conformity, leaving individuals, including psychologists, in recurring states of internal conflict and intellectual discomfort when deciding how much to compromise in their personal and professional lives. The study identifies three groups of psychologists based on their adaptability to regime demands. The first group consists of those who aligned themselves with the regime, allowing them to hold positions of leadership and shape the conceptualization of the field. The second group comprises individuals who actively opposed the regime, facing significant limitations in their educational and career opportunities, and mostly being forced to leave the profession. The third group of psychologists belongs to the apolitical gray zone. A significant portion of individuals in this largest group passively complied with established norms and constraints, accepting the restrictions imposed on the development of Czechoslovak psychology. Fortunately, thanks to the persistent efforts of the proactive members of the gray zone and their willingness to endure significant discomfort, an even deeper decline of psychology during the normalization period was prevented. The study provides insights into the topics of education, research, Western influences, and adaptation to the communist regime within Czechoslovak psychology, illuminating the intricacies of living in that historical period. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Durganand Sinha (1922-1998) was an important Indian cross-cultural psychologist whose research spanned half a century. In commemoration of Sinha's passing 25 years ago, I explore in this essay his vision of the integration of Hindu religious psychology and Western scientific psychology. In the first part of the discussion, I consider a brief history of the interaction between Indian cultures and Western scientific psychology. In the second part, I next consider the proposal of Sinha that outlines various approaches that researchers might take with respect to the indigenization of scientific psychology. In the third part, I consider Sinha's discussion of integration as the expected outcome of the process of indigenization. Sinha indicates that when a researcher establishes a successful integrated cultural research paradigm in this way, it can serve as a framework for future researchers. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Background: Groundbreaking biomedical research has transformed renal transplantation (RT) into a widespread clinical procedure that represents the mainstay of treatment for end-stage kidney failure today. Here, we aimed to provide a comprehensive bibliometric perspective on the last half-century of innovation in clinical RT., Methods: The Web of Science Core Collection was used for a comprehensive screening yielding 123 303 research items during a 50-y period (January 1973-October 2022). The final data set of the 200 most-cited articles was selected on the basis of a citation-based strategy aiming to minimize bias., Results: Studies on clinical and immunological outcomes (n = 63 and 48), registry-based epi research (n = 38), and randomized controlled trials (n = 35) dominated the data set. Lead US authors have signed 110 of 200 articles. The overall level of evidence was high, with 84% of level1 and -2 reports. Highest numbers of these articles were published in New England Journal of Medicine , Transplantation , and American Journal of Transplantation. Increasing trend was observed in the number of female authors in the postmillennial era (26% versus 7%)., Conclusions: This study highlights important trends in RT research of the past half-century. This bibliometric perspective identifies the most intensively researched areas and shift of research interests over time; however, it also describes important imbalances in distribution of academic prolificacy based on topic, geographical aspects, and gender., Competing Interests: The authors declare no funding or conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

This article aims to (re)introduce and further develop Dimitri Uznadze's theory of psychological "set" from the perspective of contemporary cultural psychology. His ideas are prominent in Georgia and other post-Soviet countries; however, they might be totally new for psychologists from other parts of the world. Uznadze, unlike Vygotksy, still awaits to be rediscovered. I discuss the main theoretical premises and features of the formation of a psychological "set," according to Uznadze, which were based on his interpretations of his rich experimental data. Uznadze conceived the psychological "set" as a holistic phenomenon determining human conduct and strongly opposed reductionist, vitalist, and behavioristic approaches. Subsequently, a more person-centered and systemic view of set formation and its relation to human conduct is briefly considered. Further directions for Uznadze's experimental data's theoretical consideration are also identified. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Magda Arnold (1903-2002) is well known for her research on emotions, motivation, and memory from a neurological, physiological, and psychological point of view. However, her works in the field of the anthropological foundations of personality are less known and discussed. The present study presents some aspects of Arnold's conception of a human's nature as being based or convergent on Aquinas's doctrine: (a) a nonreductionist conception of the human being, (b) the psychophysical unity of the person, (c) the self-ideal as it ought to be as the main factor of personality integration, and (d) God as the origin and ultimate goal of human existence. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Psychiatrist, psychoanalyst, and neurologist William Guglielmo Niederland (1904-1993) received widespread acclaim for his research on Holocaust survivors, yet his other psychoanalytic work has yet to achieve comparable recognition. In this article, I will examine the affinities between Niederland's study of the Holocaust survivors and other major works in his canon to demonstrate the cohesive nature of his worldview, philosophy, and psychoanalytic trajectory while also illuminating Niederland's portrait of the human being. This work is divided into two sections. The first section will deal with what I have termed as "the phenomenological sensitivity" which articulates Niederland's unique intellectual approach of subjectively retracing his patients' phenomenal experiences. The second section will discuss Niederland's image of the human being at the nexus of space and time, as it emerges from a comparative reading across his various writings. Ultimately, the article will present these two recurrent elements not only to help identify Niederland's integrated worldview which extends throughout, but also beyond his trauma work with Holocaust survivors. (PsycInfo Database Record (c) 2024 APA, all rights reserved).